The COVID-19 pandemic has substantially affected the lives of people living wiht HIV (PLHIV), who frequently face multiple morbidities and may be at heightened risk for COVID-19 complications, with spillover effects on other aspects as equitable access to treatment and prevention. Countries must ensure an appropriate balance between protecting health, preventing economic and social disruption, and respecting human rights to ensure that PLHIV have the same access to services as others, and that HIV-related services continue without disruption as the health system responds rapidly and effectively to COVID-19. Anyone can get infected with SARS-CoV-2 and become severely sick or die from COVID-19. However, people with underlying medical conditions or those who are immunocompromised or have a weakened immune system are more likely to get very sick, be hospitalized, need intensive care, require a ventilator to breathe, or die from COVID-19. People with HIV have higher rates of certain underlying medical conditions. The human immunodeficiency virus (HIV) weakens the immune system and can cause a person to be immunocompromised.